5-Ethyl-4-pyrrolidin-1-ylmethyl-furan-2-carboxylic acid hydrochloride
5-Ethyl-4-pyrrolidin-1-ylmethyl-furan-2-carboxylic acid hydrochloride
CAS: 1185299-46-0
Molecular Formula: C12H18ClNO3
5-Ethyl-4-pyrrolidin-1-ylmethyl-furan-2-carboxylic acid hydrochloride - Names and Identifiers
5-Ethyl-4-pyrrolidin-1-ylmethyl-furan-2-carboxylic acid hydrochloride - Physico-chemical Properties
| Molecular Formula | C12H18ClNO3 |
| Molar Mass | 259.73 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD11506486 |
5-Ethyl-4-pyrrolidin-1-ylmethyl-furan-2-carboxylic acid hydrochloride - Risk and Safety
| Hazard Class | IRRITANT |
5-Ethyl-4-pyrrolidin-1-ylmethyl-furan-2-carboxylic acid hydrochloride - Introduction
hydrochloride acid (5-ethyl-4-pyrrolylmethylfuran-2-carboxylic acid hydrochloride) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White to almost white crystal
-Melting point: about 110-120°C
-Molecular formula: C13H20ClNO3
-Molecular weight: 273.76g/mol
Use:
The acid hydrochloride is used as a pharmaceutical intermediate or raw material in the pharmaceutical field. Its fusion salt form can be used as the synthesis of antibiotic drugs.
Preparation Method:
The acid hydrochloride can be synthesized by the following steps:
1. Ethylation: Furan -2-carboxylic acid is reacted with p-ethyl bromomethanesulfonic acid to form ethyl furan -2-carboxylic acid.
2. acyl chloride: ethyl furan -2-carboxylic acid reacts with dichlorinated gastric acid to generate ethyl furan -2-carboxylic acid chloride.
3. version poly: ethyl furan-2-carboxylic acid chloride is reacted with pyrrole methylamine to generate acid.
4. salinization: react acid with hydrochloric acid to generate acid hydrochloride.
Safety Information:
There are limited specific toxicity and safety data for the acrylic hydrochloride. When handling this compound, it is recommended to follow laboratory safety practices, wear appropriate protective gloves and glasses, and ensure good ventilation.
Nature:
-Appearance: White to almost white crystal
-Melting point: about 110-120°C
-Molecular formula: C13H20ClNO3
-Molecular weight: 273.76g/mol
Use:
The acid hydrochloride is used as a pharmaceutical intermediate or raw material in the pharmaceutical field. Its fusion salt form can be used as the synthesis of antibiotic drugs.
Preparation Method:
The acid hydrochloride can be synthesized by the following steps:
1. Ethylation: Furan -2-carboxylic acid is reacted with p-ethyl bromomethanesulfonic acid to form ethyl furan -2-carboxylic acid.
2. acyl chloride: ethyl furan -2-carboxylic acid reacts with dichlorinated gastric acid to generate ethyl furan -2-carboxylic acid chloride.
3. version poly: ethyl furan-2-carboxylic acid chloride is reacted with pyrrole methylamine to generate acid.
4. salinization: react acid with hydrochloric acid to generate acid hydrochloride.
Safety Information:
There are limited specific toxicity and safety data for the acrylic hydrochloride. When handling this compound, it is recommended to follow laboratory safety practices, wear appropriate protective gloves and glasses, and ensure good ventilation.
Last Update：2024-04-09 15:18:09
